30 October 2024

Raynaud’s not just a cold weather friend

Climate Raynaud phenomenon Systemic sclerosis

Humidity, heat and air conditioning make summer a problem too.


Hot outside temperatures are associated with Raynaud’s attacks almost as bad as the cold, according to international research published in The Lancet this month.   

“In contrast to previous studies, which have highlighted challenges in cold temperatures for people with Raynaud’s phenomenon, our results underline that people with Raynaud’s phenomenon who live in hot climates also have to cope with excessive cooling in buildings, such as office buildings and shopping facilities, which they might not be able to avoid,” the authors write.  

Raynaud’s affects more than 95% of people with systemic sclerosis and is exacerbated by cold temperatures, emotional stress and ambient temperature changes.   

A multinational study correlated over 20,000 reports of severity of Raynaud’s phenomenon symptoms from more than 2000 patients with systemic sclerosis, with the temperature, humidity and wind chill factor in the area at the time. The participants were from the US, UK, Canada, France, Spain, Mexico and Australia, mainly women (88%) and white (82%), with a mean age of 55.   

As expected, severity was worst at -25C. Symptoms improved very slightly between -15C and 5C. The improvements were marked between 5C and 25C.   

This was the optimum temperature range in terms of symptoms.   

After that, severity began to increase again and was worse at 35C and 40C, although not as bad as at the coldest temperatures.   

The association was similar across countries and scleroderma subtypes.  

“Overcooling of buildings (including in office buildings and shopping facilities), which involves maintaining air temperatures below recommended comfort temperatures, is common in hot and humid climates,” the authors said.   

“It is also possible that evaporation might play a role in Raynaud’s attacks. We found that predicted Raynaud’s phenomenon severity can increase by 2–3 points on a 0–10 scale between 25C and 40C. These findings will be useful for clinicians and patients to identify periods of heightened risk for Raynaud’s attacks that might occur despite steps taken to reduce exposures.”  

Local results from the Australian Scleroderma Cohort Study, also published this month, in a brief report in Arthritis Care and Research, similarly showed that symptoms were worse in cold temperatures, high relative humidity, and lower daily evaporation “suggesting an important role for dry warmth in managing this condition”.  

“Worsened RP was strongly associated with telangiectasia, calcinosis and digital ulceration (DU), as well as demonstrating an association with anti-centromere antibody and gastro-oesophageal reflux disease (GORD) and a negative correlation with diffuse disease. Worsened RP was also strongly associated with worse [health-related quality of life],” the Australian authors say.  

The Lancet Rheumatology, October 2024  

Arthritis Care and Research, 17 October 2024